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lipopeptide antibiotic daptomycin  (Cubist Pharmaceuticals)

 
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    Cubist Pharmaceuticals lipopeptide antibiotic daptomycin
    Lipopeptide Antibiotic Daptomycin, supplied by Cubist Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lipopeptide+antibiotic+daptomycin/lipopeptide+daptomycin/pm27328129-60-23-14
    Average 90 stars, based on 1 article reviews
    lipopeptide antibiotic daptomycin - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Bacteria:

    Article Title: Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus
    Article Snippet: .. The lipopeptide antibiotic daptomycin is active against a wide range of gram-positive bacteria (Cubicin prescription information, 2005; Cubist Pharmaceuticals, Lexington, MA) ( 4 ) and is believed to possess a novel mechanism of action that does not involve cell lysis. .. Instead, the lipophilic acyl tail of daptomycin is inserted into the cytoplasmic membrane of the bacterium, leading to potassium efflux; destruction of the ion-concentration gradient; membrane depolarization; inhibition of protein, DNA, and RNA synthesis; and finally cell death (Cubicin prescription information, 2005; Cubist Pharmaceuticals, Lexington, MA) ( 5 , 11 , 13 ).

    Lysis:

    Article Title: Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus
    Article Snippet: .. The lipopeptide antibiotic daptomycin is active against a wide range of gram-positive bacteria (Cubicin prescription information, 2005; Cubist Pharmaceuticals, Lexington, MA) ( 4 ) and is believed to possess a novel mechanism of action that does not involve cell lysis. .. Instead, the lipophilic acyl tail of daptomycin is inserted into the cytoplasmic membrane of the bacterium, leading to potassium efflux; destruction of the ion-concentration gradient; membrane depolarization; inhibition of protein, DNA, and RNA synthesis; and finally cell death (Cubicin prescription information, 2005; Cubist Pharmaceuticals, Lexington, MA) ( 5 , 11 , 13 ).

    other:

    Article Title: Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus
    Article Snippet: Instead, the lipophilic acyl tail of daptomycin is inserted into the cytoplasmic membrane of the bacterium, leading to potassium efflux; destruction of the ion-concentration gradient; membrane depolarization; inhibition of protein, DNA, and RNA synthesis; and finally cell death (Cubicin prescription information, 2005; Cubist Pharmaceuticals, Lexington, MA) ( 5 , 11 , 13 ).

    Drug discovery:

    Article Title: Polymyxins: a new hope in combating Gram-negative superbugs?
    Article Snippet: .. To date, the most advanced of these polymyxin drug discovery programs was undertaken by Cubist Pharmaceuticals, the company that developed and marketed the lipopeptide antibiotic daptomycin for treatment of Gram-positive infections. ..



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    Infection Parameter
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    Image Search Results


    Infection Parameter

    Journal: Journal of Cardiothoracic Surgery

    Article Title: Treatment of gram-positive deep sternal wound infections in cardiac surgery -experiences with daptomycin-

    doi: 10.1186/1749-8090-6-112

    Figure Lengend Snippet: Infection Parameter

    Article Snippet: The first in a novel class of cyclic lipopeptide antibiotics daptomycin (Cubicin; Cubist Pharmaceuticals, Inc., Lexington, MA), has already been proven to be effective in the treatment of bacteremia and endocarditis caused by MRSA and several case reports document about its effectiveness in the field of cardiac surgery [ - ].

    Techniques: Infection

    Laboratorial data

    Journal: Journal of Cardiothoracic Surgery

    Article Title: Treatment of gram-positive deep sternal wound infections in cardiac surgery -experiences with daptomycin-

    doi: 10.1186/1749-8090-6-112

    Figure Lengend Snippet: Laboratorial data

    Article Snippet: The first in a novel class of cyclic lipopeptide antibiotics daptomycin (Cubicin; Cubist Pharmaceuticals, Inc., Lexington, MA), has already been proven to be effective in the treatment of bacteremia and endocarditis caused by MRSA and several case reports document about its effectiveness in the field of cardiac surgery [ - ].

    Techniques: